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Dysuria means pain, burning or stinging while passing urine. It is one of the most common urological symptoms and it is almost always assumed to be a urinary tract infection. Frequently it is, but a substantial minority of cases are caused by something else entirely, and those patients often take repeated courses of antibiotics that were never going to help.
Infective causes
1. Bacterial cystitis, the commonest cause overall. See UTI treatment.
2. Urethritis from chlamydia, gonorrhoea or other sexually transmitted infections, particularly with discharge.
3. Prostatitis in men, with perineal pain and urinary symptoms.
4. Vaginal infections in women: candidiasis and trichomoniasis, which cause burning as urine passes over inflamed vulval skin rather than infection of the bladder itself.
Non-infective causes
5. Bladder or urethral stones passing through.
6. Post-menopausal urogenital atrophy, where thinned tissue burns without any infection. Very commonly misdiagnosed and repeatedly treated with antibiotics.
7. Interstitial cystitis / bladder pain syndrome, causing chronic burning with urgency and a persistently sterile urine culture.
8. Chemical irritation from soaps, intimate washes, douches, spermicides and bubble baths.
9. Benign prostatic hyperplasia and urethral stricture in men.
10. Bladder tumour, particularly where there is painless blood in the urine alongside irritative symptoms.
11. Dehydration and highly concentrated urine, a genuinely common cause in Indore’s summer.
1. Burning at the start of urination suggests a urethral cause
2. Burning at the end of urination with suprapubic pain suggests bladder involvement
3. Burning with fever, chills and flank pain suggests kidney infection and needs urgent care
4. Burning with urethral discharge suggests a sexually transmitted infection
5. Burning with external vulval soreness suggests a vaginal or skin cause rather than a bladder one
6. Chronic burning with a repeatedly negative culture suggests interstitial cystitis or atrophy
See a doctor if burning lasts more than 48 hours, recurs frequently, or is accompanied by fever, flank pain, blood in the urine, urethral discharge or inability to pass urine. Any burning in a man should be evaluated, as should burning during pregnancy. If you have had several courses of antibiotics without lasting relief, the working diagnosis is probably wrong and the condition needs re-evaluation rather than another prescription.
1. Establish the cause: Urine routine and culture, and where relevant urethral swab, STI screening, vaginal examination, blood sugar, ultrasound with post-void residual and, in selected cases, cystoscopy.
2. Targeted antibiotics: Guided by culture and sensitivity rather than chosen empirically, given the level of resistance in India.
3. Treat sexually transmitted infection properly: Both partners, full course, with a test of cure. See STD treatment.
4. Antifungal treatment for candidiasis, and treatment of the vulval skin rather than the bladder where that is the source.
5. Local oestrogen therapy: Highly effective for post-menopausal burning, and the correct treatment for a group of women who are otherwise given antibiotics indefinitely. See vaginal dryness treatment.
6. Bladder pain syndrome management: Dietary triggers, bladder training, pelvic floor physiotherapy and specific medication.
7. Treat obstruction and stones: Prostate treatment, stricture management or stone removal.
8. Symptomatic measures: High fluid intake, urinary alkalinisers, and stopping all soaps, intimate washes and douching.
An untreated bladder infection can ascend to the kidney within days and cause sepsis, particularly in diabetics and the elderly. Untreated chlamydia and gonorrhoea frequently cause minimal symptoms yet progress to pelvic inflammatory disease and tubal infertility in women and to epididymitis and urethral stricture in men. And on the other side, repeatedly treating a non-infective cause with antibiotics leaves the real problem, whether atrophy, a stone, a stricture or a bladder tumour, entirely unaddressed while resistance builds. Getting the diagnosis right the first time is what avoids both paths.

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