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Haematuria means blood in the urine. It may be visible, turning the urine pink, red or cola-coloured, or microscopic and detected only on a urine test. The most important principle in urology regarding this symptom is short and worth memorising: painless visible blood in the urine is bladder cancer until proven otherwise, and it must be investigated even if it happens only once and clears completely.
Bladder tumours bleed intermittently. The bleeding stops on its own, the urine returns to normal, and the patient concludes the problem has resolved. It has not. This pattern of a single painless episode followed by weeks or months of normal urine is the classic presentation of bladder cancer, and it is the single commonest reason these tumours are diagnosed late in India. One episode warrants a full evaluation.
1. Urinary tract infection: Usually with burning and frequency.
2. Kidney or bladder stones: With severe colicky loin-to-groin pain. See kidney stone treatment.
3. Bladder and kidney tumours: Classically painless, and strongly associated with smoking.
4. Benign prostatic hyperplasia and prostate cancer in men.
5. Kidney disease: Glomerulonephritis and IgA nephropathy, often with protein in the urine and swelling.
6. Trauma to the kidney, bladder or urethra.
7. Urinary tuberculosis: Still an important cause in India, presenting with sterile pyuria and haematuria.
8. Medication: Blood thinners, which may unmask an underlying lesion rather than being the sole cause.
9. Strenuous exercise, and menstrual contamination in women.
10. Non-blood causes of red urine: Beetroot, certain drugs such as rifampicin, and food colourings. A dipstick and microscopy distinguish these immediately.
1. Painless visible haematuria at any age
2. Age over 40, or any age with a smoking history
3. Blood clots in the urine
4. Associated weight loss, loss of appetite or a flank mass
5. Inability to pass urine due to clot retention, which is an emergency
6. Occupational exposure to aniline dyes, rubber or petrochemicals
7. Persistent microscopic haematuria on repeated tests
See a urologist for any episode of visible blood in the urine, without waiting to see whether it recurs. Seek emergency care if you cannot pass urine, are passing large clots, or have fever with flank pain. Persistent microscopic haematuria found on a routine test also warrants evaluation rather than being repeated indefinitely.
1. Confirm it is blood: Urine routine and microscopy, which distinguishes true haematuria from pigment causes and identifies red cell casts pointing to kidney disease.
2. Urine culture and cytology: To exclude infection and screen for malignant cells.
3. Imaging: CT urography is the standard, assessing the kidneys, ureters and bladder in one study. Ultrasound is used where CT is unsuitable.
4. Cystoscopy: Direct inspection of the bladder, and the only reliable way to exclude a bladder tumour. This is the step most often skipped and the one that matters most.
5. Blood tests: Renal function, PSA in men, and coagulation studies where relevant.
6. Treat the cause: Antibiotics for infection, laser or endoscopic treatment for stones, TURBT for bladder tumours, prostate treatment for BPH, nephrology referral for glomerular disease, and anti-tubercular therapy for urinary tuberculosis. Our urology team handles the full pathway from evaluation to definitive treatment.
Bladder cancer is highly curable when it is confined to the bladder lining, and is treated endoscopically with a good long-term outlook. Once it invades the muscle wall, treatment escalates to radical surgery or chemoradiotherapy and survival falls substantially. The interval between those two stages is measured in months, and it is exactly the interval most patients spend waiting to see whether the bleeding returns. Similarly, an obstructing stone left because the pain settled can silently destroy a kidney, and untreated glomerular disease progresses to chronic kidney failure. Blood in the urine is a symptom that repays prompt investigation more than almost any other.

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