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Appendicitis is inflammation of the appendix, a small blind-ended tube attached to the beginning of the large intestine. It is the most common surgical emergency of the abdomen worldwide, and the one condition where the difference between a straightforward daycare operation and a serious illness is measured in hours rather than weeks.
Appendicitis has a characteristic and highly recognisable evolution, and knowing it can save a great deal of time:
1. Vague, poorly localised pain around the navel, often described as colicky
2. Loss of appetite, which is almost always present, followed by nausea and often one or two episodes of vomiting
3. Over the next 6 to 24 hours, the pain shifts to the right lower abdomen and becomes sharp, constant and well localised
4. Low-grade fever develops
5. Pain worsens with coughing, walking, driving over bumps and any jarring movement
That migration of pain from the centre to the right lower quadrant is the single most useful diagnostic feature.
1. Obstruction of the appendix lumen by a faecolith (hardened stool), which is the commonest mechanism
2. Lymphoid hyperplasia following a viral infection, particularly in children and young adults
3. Parasitic infestation, which remains relevant in India
4. Rarely, a tumour of the appendix or caecum in older patients
5. Low-fibre diet, which is a contributing dietary factor
1. Right lower abdominal pain with tenderness at McBurney’s point
2. Loss of appetite, nausea and vomiting
3. Low-grade fever, rising if perforation occurs
4. Constipation or diarrhoea
5. Guarding and rebound tenderness on examination
6. Warning of perforation: sudden brief relief of pain followed by severe generalised abdominal pain, a rigid abdomen, high fever and rapid pulse. This indicates peritonitis and requires immediate hospital care.
Presentation can be atypical in children, elderly patients, pregnant women (where the appendix is displaced upwards) and those with a retrocaecal appendix, which is exactly why clinical suspicion plus imaging matters more than a textbook history.
Go to a hospital the same day for abdominal pain that has shifted to the right lower quadrant, particularly with loss of appetite and fever. Go immediately for severe pain with a rigid abdomen, high fever or persistent vomiting. Do not take painkillers, antibiotics or laxatives at home and wait, as this masks the picture, delays diagnosis and increases the risk of perforation. Do not eat or drink anything once appendicitis is suspected, since surgery may be needed within hours.
1. Diagnosis: Clinical examination, total leucocyte count and CRP, ultrasound abdomen, and CT where the picture is unclear. MRI or ultrasound is used in pregnancy.
2. Laparoscopic appendicectomy: The standard treatment. Removal of the appendix through three small incisions, with less pain, a shorter stay, faster recovery and a lower wound infection rate than open surgery. Most patients go home within 24 to 48 hours.
3. Open appendicectomy: Used where there is extensive perforation, dense adhesions or a large appendicular mass.
4. Antibiotic-first management: Selected patients with early, uncomplicated appendicitis can be treated with antibiotics alone, but a meaningful proportion recur and eventually need surgery. This approach is chosen carefully, not by default.
5. Appendicular mass or abscess: Managed initially with antibiotics and drainage, with interval appendicectomy performed several weeks later once inflammation has resolved.
6. Emergency surgery with peritoneal lavage: Where perforation and peritonitis have already occurred.
Appendicitis is unusual among surgical conditions in how quickly delay changes the outcome. An inflamed appendix typically perforates within 48 to 72 hours of symptom onset, and the risk rises sharply after 24 hours. Before perforation, appendicectomy is a short keyhole operation with a one-day stay and a very low complication rate. After perforation, the same patient faces peritonitis, a longer and more difficult operation, intra-abdominal abscess, prolonged antibiotics, a hospital stay measured in weeks, adhesions that can cause bowel obstruction years later, and a genuine risk to life. There is no other common condition where a few hours of hesitation costs so much.

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